New Delhi, May 12 (KNN) The CSIR-Institute of Himalayan Bio-resource Technology (CSIR-IHBT), Palampur has signed a MoU with its industry partner - Phyto Biotech, Kolkata, to formalize technology transfer for production of unique enzyme which may be used in developing anti-ageing cream. 
 
Besides cosmetic, the enzyme — Super Oxide Dismutase (SOD) — may also be used in food and pharmaceutical industries for end applications like extending shelf life of fruits and vegetables.  
 
This enzyme will also be useful during cryosurgery and preservation of organelles (specialized sub-unit within cell that has a specific function). The cryosurgery is an application of extreme cold to destroy diseased tissue.  
 
“The licensing has brought together the CSIR and the industry to enable commercial production of desired standard SOD so as to create a global niche for the country", said an official statement of the ministry of science and technology. 

The enzyme was discovered by CSIR-IHBT during a survey at an altitude of over 10,000 feet in the Western Himalayan region from Potentilaastrosangunia plant growing under snow cover. 

"Persistent hard work over the years has resulted in the isolation of the SOD gene", said the ministry. 

Thereafter, a protocol was developed for cloning of the gene in E Coli. The enzyme, thus produced, retained the same unique feature as that of the native plant. 

"Applying the knowledge of bioinformatics, the enzyme has been further engineered by mutation of a single amino acid to increase its consistency and thermo-stability", it said. 

The characteristic features of this SOD lies in its stability and functionality ranging from sub-zero to high temperature (above 40°C) with varying specific activity. Owing to its high antioxidant properties and multiple uses, the SOD enjoys high demand and price in the global market. (KNN Bureau)